Simbec Research Limited

SIMBEC RESEARCH:
Over 25 years Experience in Clinical Research

* PHASE I STUDIES
Comprehensive experience from First-Into-Man through to Bioequivalence.
96 Phase I beds.

* PHASE II AND III CLINICAL TRIALS
Proven track record from selecting appropriate investigators through clinical monitoring to data management. Simbec is internationally focused, including offices in Central & Eastern Europe.

* CENTRAL LABORATORY
GLP and CAP (US) accredited laboratories. Services include customised documentation, investigator support and remote data access.

* BIOANALYTICAL
GLP compliant laboratories. Wide-ranging techniques from immunoassay to LC-MS-MS for drug assays in support of Phase I - IV.

* REGULATORY AFFAIRS
Regulatory expertise and experience with both pharmaceuticals and devices registration.

* GAMMA SCINTIGRAPHY
Pharmaceutical imaging for proof of concept.

Activity:

- Contract Research
- Regulatory Affairs & Legal Services
- Research & Development

Product / Technology type(s) covered:

- API / chemicals
- Bio
- Cosmoceuticals
- Curative
- Devices
- Diagnostics
- Drug delivery
- Enzymes
- Generics
- FP (finished products)
- NCE (new chemical entities)
- OTC (over the counter drugs)
- Pharmaceuticals / Therapeutics
- Phyto
- Nutritionals / Vitamins
- Prescription drugs (Rx)
- Preventive
- Proteins
- Reagents
- Technology

Therapeutic targets:

- Aging
- AIDS
- Allergy
- Alzheimer's Disease
- Arthritis / Rheumato
- Asthma
- Cancer
- Cardiovascular
- Central nervous system
- Cough / Cold
- Dermatology
- Diabetes
- Gastrointestinal
- Genetics
- Geriatrics
- Hematology
- Infectious Diseases
- Men's Health
- Mental Health
- Neurology
- Obesity
- Oncology
- Ophthalmology
- Orthopedics
- Pain
- Pediatrics
- Radiology
- Reproductive Health
- Respiratory Medicine
- Stroke
- Surgery
- Tonics
- Transplant
- Urology
- Women's Health

Markets Covered

a. HeadQuarter: United Kingdom

b. Continent(s) active: Europe , North America , Far East , Near/Middle East , Asia , Central/South America , Australia/New-Zealand , Africa

c. Countries active: Main: UK, US, Japan, France, Spain, Israel

Corporate data:

Number of Employees: 120

Turnover:

Amount:	Year:	Currency:
10 million	2000	US Dollar

Year founded: 1976

Partners / Alliances: RCC (Switzerland, Preclinical)
Simbec Scintigraphics (UK,Joint-Venture)
Simbec-IPC (France, Clinical Trials & Regulatory)
Simbec-Israel (Phase I - III Trials)
Simbec-Spain (Phase I Studies)